From the NYT bestselling author of Bel Canto and Run, a major and explosively ambitious new novel, set in the Amazonian jungle, both a gripping adventure story and a profound investigation of difficult human choices.

Marina Singh is a research scientist at Vogel, a pharmaceutical institute in Minnesota, inconveniently in love with her boss, Mr. Fox . When one of her colleagues is reported to have died while following up on the progress of a field team based in Brazil, Marina is dispatched by Mr. Fox to the Amazon to uncover the truth of his death. And his widow wants his effects. She travels to Manaus, then down into the Amazonian delta, deep into the dense, dark, insect-infested jungle. The research team is looking into the development of a new miracle drug that could revolutionize Western society. A local tribe has the bark of a certain tree, it yields a substance which allows them to conceive late into middle age: many of the women are getting pregnant into their sixties and seventies. The problem is that the team is taking too long: they have been silent for two years, and Marina has been tasked to find out what is holding back their progress. The second problem is more serious: the team is being headed up by the daunting figure of Marina Swenson, an eminent and fiercely uncompromising scientist who was once Marina’s colleague, and towards whom Marina has very complicated feelings.

What Marina learns will change her life. In a novel that is packed with amazing twists and surprises, Ann Patchett returns with immense confidence to a broad canvas, teeming with atmosphere and characters and rich with narrative. Remarkable events - fights with anacondas; encounters with cannibals; deaths; re-births - and profound moral decisions come together in a novel that will enthrall her many readers and fans, and is guaranteed to be a major bestseller.

Ann Patchett is the author of novels, works of nonfiction, and children's books. She has been the recipient of numerous awards including the PEN/Faulkner, the Women's Prize in the U.K., and the Book Sense Book of the Year. Her novel The Dutch House was a finalist for the Pulitzer Prize. Her work has been translated into more than thirty languages. TIME magazine named her one of the 100 Most Influential People in the World. President Biden awarded her the National Humanities Medal in recognition of her contributions to American culture. She lives in Nashville, Tennessee, where she is the owner of Parnassus Books.

“An engaging, consummately told tale.” — New York Times

“Emotionally lucid. . . . Patchett is at her lyrical best when she catalogues the jungle.” — The New Yorker

“This is surely the smartest, most exciting novel of the summer.” — Washington Post

“The Amazon setting is something Patchett does rather marvelously.… The book is serious, but also so pleasurable that you hope it won’t end.” — NPR

“Outlandishly entertaining…[with] a brilliantly constructed plot.” — Elle

“Packs a textbook’s worth of ethical conundrums into a smart and tidily delivered story. . . . Ms. Patchett presents an alluring interplay between civilization and wilderness, between aid and exploitation.” — Wall Street Journal

“The large canvas of sweeping moral issues, both personal and global, comes to life through careful attention to details, however seemingly mundane—from ill-fitting shoes and mosquito bites to a woman tenderly braiding another woman’s hair.” — O, the Oprah Magazine

“A spellbinder from bestselling author Patchett. . . . Thrilling, disturbing and moving in equal measures—even better than Patchett’s breakthrough Bel Canto.” — Kirkus Reviews (starred review)

“A superbly rendered novel. . . . Patchett’s portrayal is as wonderful as it is frightening and foreign. Patchett exhibits an extraordinary ability to bring the horrors and the wonders of the Amazon jungle to life, and her singular characters are wonderfully drawn. . . . Powerful and captivating.” — Library Journal (starred review)

“A thrilling new novel. . . . The world imagined in this novel is unusually vivid. . . . Reading State of Wonder is a sensory experience, and even after it’s over you’ll keep hearing the sounds of insects, and your own head will still be hot.” —

“A thrilling new novel. . . . The world imagined in this novel is unusually vivid. . . . Reading State of Wonder is a sensory experience, and even after it’s over you’ll keep hearing the sounds of insects, and your own head will still be hot.” — MORE Magazine

“Patchett makes the jungle jump off the page…This is Patchett’s best effort since The Patron Saint of Liars and, yes, that includes Bel Canto” — Shelf Awareness

“Extraordinary. . . . Is there nothing the prodigiously talented Ann Patchett can’t do? . . . Patchett’s last knockout pages proceed full-speed ahead, with more twists and turns and trachery than the Amazon River. Nothing is as it seems, and the ending is as shocking as it’s satisfying.” — Boston Globe